What Is ALIMTA® (pemetrexed for injection) Approved For?
ALIMTA is approved by the FDA in combination with KEYTRUDA® (pembrolizumab) (an immunotherapy) and platinum chemotherapy (carboplatin or cisplatin, two other chemotherapy drugs) as the first treatment for nonsquamous non-small cell lung cancer (NSCLC) that has spread with no abnormal EGFR or ALK genes.*
ALIMTA is not appropriate for people who have a different type of NSCLC called squamous cell.
* Epidermal growth factor receptor (EGFR) is a tumor marker found in some people with nonsquamous NSCLC. It is found on both normal and tumor cells and is important for cell growth. Anaplastic lymphoma kinase (ALK) is a protein that may be involved in cell growth. Changes to the ALK gene have been found in some types of cancer, including nonsquamous NSCLC.
Important Safety Information for ALIMTA
What is the most important information that I should know about ALIMTA?
ALIMTA can cause serious side effects including:
Who should not take ALIMTA?
ALIMTA may not be appropriate for some patients. If you are allergic to pemetrexed, tell your doctor because you should not receive it. It is not known if ALIMTA is safe and effective in children.
What should I tell my healthcare provider before receiving ALIMTA?
How is ALIMTA given?
What are the possible side effects of ALIMTA?
The most common side effects of ALIMTA when given alone are:
The most common side effects of ALIMTA when given with cisplatin are:
The most common side effects of ALIMTA when given with pembrolizumab and platinum chemotherapy are:
ALIMTA may cause fertility problems in males. This may affect your ability to father a child. It is not known if these effects are reversible. Talk to your healthcare provider if this is a concern for you.
Your healthcare provider will do blood tests to check for side effects during treatment with ALIMTA. Your healthcare provider may change your dose of ALIMTA, delay treatment, or stop treatment if you have certain side effects. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all the side effects of ALIMTA. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
ALIMTA is available by prescription only.